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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f148f4220dcf8b1db4eb384f1917f1a915e23eb2e789915479bdb7772deacdc' 
  AND token = 'bNlwksPLC2zfJuNjR+1pH9M3kAVnfnPf/wDP8QBUGmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}