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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8abfbd2f4e56920a86dd600ba4433bcc79e2f49d2755adfb19bc6de5987f4c87' 
  AND token = 'MWCeYYpU2xfpagVk+4F0i3F4cZ4HbtcocyqZoVcQSQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}