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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0ac844d06e9a7946e73deea0adc6ff0155c4e0e127652f69d097b398971aa7' 
  AND token = 'VxzV0gLlGtVF1Y/v96R1jFdM8WzAPAlqI0MVs2fWr54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}