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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee1af7ff663d6f73f5b5825871b03aa78c9a12a7ef3766b4f76e3c8271722fb' 
  AND token = '/1V+1XXjZny86hHacflLaTQOFapEbfHjUd2D8htAjkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}