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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f4dec15749a20d25861b60ba0f1cd2cb0fd2d61b9cfc641ec92c49521c9a7d' 
  AND token = 'YzTlczdCj/IrYlQXykvH4wjnwl1ta9qLiflu5EEsq5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}