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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2ef6a4d3566049011405d469004e446c42edbc27c08c685d974831b4fcc4d4' 
  AND token = '0mXmeNLSHvGy3o6Av4Nxkj7v2k8LTY60kaG38Ht6eO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}