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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5f2eed76f4a1697694297cca536ea55fcc390d19fde8c6d2922f9860c90937' 
  AND token = 'SAifeoYgxSzN1vpoGZ997u7WPy5vcFNcQMX0LJwF1pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}