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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0cc2401a09e9d457324fb9f9edb0c26da15d5d2db774e0e7c6375965f9b010' 
  AND token = 'Uuc9eemhq7jJgBJCoDAC3OMmk1lKtxVOS05L2pcxW4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}