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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d6b3913118fc7da28ed2d3faf9f889e195e4df5512435d0e45b208202022be' 
  AND token = 'ZkdqHTD++kwB8seFGdoB6nJe3tpwAcXslwEbf1Gs7X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}