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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22dd69412991caeeb3071af7d03d77f8c151fb0523aceb89b1c9d0f28b22b7c' 
  AND token = 'kd0RGd7HazdBKhXLpsKvHkPf9vzF4W7WjHVYHXiIiaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}