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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd300105637c3da4c8e005a5c670e259d50ce535cde28ac51b9fb47cd8c05936c' 
  AND token = 'TFfuh2AUy2GOioAJWbCZ1DQieZlsmGnahJpcFqgnW3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}