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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75041327b60eeef6b96f26472bd97e41c75a520f646993ee4580df358b583d0c' 
  AND token = 'M41WTLkoETuzz+PixCAbsenpqSfpTBt5lV0Mrd5brzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}