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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c27c8470314462ba8fe008f1f0d5d6b23a8ae32729094fa9c5383c236f1c786' 
  AND token = 'MMyFwOM5hgzh0kXGUABSwl+7W7nV1ah7BqU93p7L0/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}