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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1eac1e56771e0e7db24d06c1b35cc2d093646a0a02401b7670c156b33a0b6c' 
  AND token = 'pi1m2cexUiF62iRflS0pjTVGmc1H2SLszMF6O/ge5e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}