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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '993265bb8545099ecf07731b243ec6d5ff3f3c131b985eb5792a828095ec6d5b' 
  AND token = 'VPSad0QVZpP+4s+ICx93BfZU4UFcaQ23gTePL7rG/rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}