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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157d0e8d968a0cc71a0d37f114c90d27b76bd9cf54e5dc9c02d409565f50b407' 
  AND token = 'I4SQGYwPteI+Aj6ZZa2RfPIKuzJc0jN64Q9KoIGN0Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}