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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d049424b26cb8cc15f1aaa868d6664a4f481342798d124105daabdb51735ad4' 
  AND token = '/vkFUMuv+d1L0S0Ijpzrs3wBrijpHQld9cm57YJ3dns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}