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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1f34a48aa3773996b4760b321c37572011694ab3b6606188808791c577d563' 
  AND token = 'txGD8UXUPOAiTiiD41j/b6wnXgDSZB6tgOLu5cNDADc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}