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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c1a1ec2affe58bafbae613ad9aae48d687e6eb5c356ca7642ee53bdb48ffbf' 
  AND token = 'JYYPtScmSPP7IoSflEiOBFgLPy+/PKNE7xgQdKyB1a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}