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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ad9359cf86b1232b30019f19f4d9f54de7fd9a06f9440a9be11c42ec686ed1' 
  AND token = 'julKSDhhU+EBrdaCzmCAmYW4gUFkWGF9n4d9xGBKr+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}