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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60385b9fc5ce0835626b234b40362fe1decadb0e0bbeb21c4ed0fe41b0e6077' 
  AND token = 'TQ+NstH9hPorn/PaekESkeeW1nMbtb4zXcJiEcSxBsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}