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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a253366bbdf0a1d777a33279cd3c505c05633f3969892c774c27a2981eef65' 
  AND token = 'ZAi4Amm2lC2L6MG7m3xLVgZadT2GiyanD1YgyFXpKYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}