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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a385430f6724f32b96e50eaca76e703adabc53fe05eab32323b5bb49a8d2c260' 
  AND token = 'TBedORfWhNH7cIZCrnwE3yE031DRZd5XZoQcDaGxiH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}