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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54993db838bbd051d301a0f9385ba993132a37c38f2639d0bf583d68f4fc5121' 
  AND token = '4ZDWo+F8l4xClL0YyDIggJXleEm8P4pJh8YBGRHM0Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}