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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b18692560073454b8499b41eeef0a3fd3f192158082d1fd2194839d9afa494' 
  AND token = 'hUERf0jnNC9+ZgqxG5uxDzzKT08rHSMOoCRo3E5f3YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}