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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eacac82940f09b7b119e4a79d0b69c1e9ebde67c851fa3c92321f3a149e6de0' 
  AND token = 'oHQxChpd6H1sd6htn4GDfUyJXvbBtjTIFFySgR+58mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}