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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a41f564cb70e53f58a1235ae25580ed64d7ba6bbdd5a7fa7e419cc51e3d5940' 
  AND token = 'njV/iYpsahb7bxG9s2qaS3eRWdAqH+oPr3XxLy+6ng0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}