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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf6d4afd374244b30b0a76b6c5e7d8de7ada2e2ed561aeda2e82e76256addb33' 
  AND token = 'vZepa/eO8Xr4wYJUFwUGKlSJ7jvieMSN/UC8K5tNRLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}