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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb46e3ee4d82073ac8ad5e252a262f34fcf6ea77f5989023644371be69c8289' 
  AND token = 'Eizh9HQiUpzkeh0RZ1KPmGym+B5BmoXewXbHxPK8AbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}