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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080bd53161b8dd017621e4e9866503a5adaed8f0d069f7b3f3bbc339d5c688ab' 
  AND token = 'otQH1/qeUToTCyaHDs5relN61Yw09YkeAAHM1D5MtfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}