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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21c99c82ba3c1a409e342c4e9c5c9bde3e24327275244fc7675b7b94d3d7ca1' 
  AND token = 'qrjk9q8lfiJkJfX9EMms06KNowS13aaSJ9AmIR4jPhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}