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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e154b29a201d578268e0ffd2f2f67eb22c8341d08493a6abc408a8fd8899dd' 
  AND token = 'BlaHYnNpno+qkcwFGO2gDB1QEsi95uA13IZaw0wfBR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}