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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72349a6e6da4435597ce8049f2849e390783d06e00a055b99a43243a06cfd742' 
  AND token = 'rd2+EwDEcpYo/Xe2xConvY2zbwfc1I2EB9MIXTqX+FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}