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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd022f1f0268c58e9f43424f151578627636c1f6afdf5e29f642cc5c1530f7ea' 
  AND token = 'iNJi9XQPjb+F/bzfLiXw/PjwG2KWHpw1UezOKS5p5s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}