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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d5c42b6af005b34127b8404cd7ce10b8d1c5e0b4e2978b9f6232bca387ce8c' 
  AND token = 'T2Fh6Acup0P2R3wsYPmA4Ud1rT7TDUWNvRiJxdAz6nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}