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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0019b8136d94bedd8460d04bcb9d8cb311d869d9f4eb5c919c3519bd372aa8' 
  AND token = '2DjhLchq2RxeCS3fMK5grG1rfvUtRyfRy3lto5Yy2HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}