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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0a7f0b876be4240506f5f42e5d0cd1267c6f0a0ede4860f58ae0387c2586dc' 
  AND token = 'mZ2CHrE9Qv5QC9P1rYk1bnlzCPJd5PtY0CPZh3oL1io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}