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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbf8957c0fce0cc2e9c3200b92557cf91179066db34df3104b6ec65466f94ae' 
  AND token = 'TlUiP2s2fxNuBKOk1IWCna1kq/ETd2nhrEttl2zh8Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}