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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd0efe0b66120f8ab2df6cf8f6aba3999e4a285049feca93de5180b4514f20ae' 
  AND token = 'POWz21xX+8zglSItmMWBZ5Adr3kKt2bRRmXUzYSrlMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}