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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2ac8214a7d86e52ca85744e5e63c766aacbfe34d5d8739ed5ac9a33565294c' 
  AND token = 'UTz8TMbr4Ou3BhFHAg80WNTO2OfkBD2OXnom6aTozg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}