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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1774f82d9b9fee9f3d8afb796f17d767f76788e67ff912b1621db826005b6a29' 
  AND token = '0PVaAXQhmJ1EunNSdveNgPfoCeIIk5p+ncxEauajv3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}