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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a31e734f2aa793359fd8c4c5eabf52d32520f7e56bed95a9b773473e7dc9cc' 
  AND token = 'fsCt/MD2d6HQ8Xxpp2iYNkNZ6QYAcSmjHhZJgYbkueY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}