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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44dc1fd2655c146afd0cfc96a220acb5605c7c7911c1a8dde65f2dda5b69787c' 
  AND token = 'A8RGW+dVEeEnRmGqn+b9P1eF1eOtbuu/PQ35sU8ygMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}