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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee344b4cfee0839c61f0e14e015b7406a203d615966c9249de19beb1214d4df0' 
  AND token = '4Cf5cKkYcMvvuRgqjcF+5VNnB9tHMs2FLeRq0DYDg+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}