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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8341688fbae66d8a81c611b4b479d38cb65a0a1c16f34bc1845c17f5df7d22' 
  AND token = 'P0TwuT8Wy/i/vNLWxzI25rXRHaYUQKmbAfNgaGR538M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}