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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed10b3a9783f3927e9b2020500621db8daa37e1d46ac9c2a35f5d257d16f7a4' 
  AND token = 'xJiAKxAvD/LlyRRCeQCzPgy9VQGkDw6rda9RZIbe0C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}