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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f0f82a9731ae767417c46240446548472a72a6867c63e15e6617977160bd1f' 
  AND token = 'VkmRbDVCn3nuo/cQ5Cj46FnNgk/MirE7HuTwrZAcDjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}