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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6f24eceec3c80fdcb19b2107fb654b56f3656a66b0fa6e849622b26bf033d3' 
  AND token = '5eTT3SltwfWTeIY7/Ue0/jQaxFl7uc089+UkPYAsMhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}