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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0db3ab984064fc65692df6672aa4f7a41ffd50e7715275e3424e7f29ee1bfc5' 
  AND token = '6D18+pvuL50/LoUPR4yU1yunS+7CR8pvCNgrcGY4hAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}