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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce9e435fb3907d9a0b776c59e870d88c340af5aa1087e10025bf9a0d9624398' 
  AND token = 'NV4bzl+FSG9ht6g+LTcecUx1L38qpe7D7V8XmVjfsM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}